TGFreseptorit
TGFreseptorit are a family of transmembrane proteins that play a crucial role in cellular signaling pathways. They are responsible for binding to transforming growth factor beta (TGF-beta) ligands, initiating a cascade of intracellular events. There are three main types of TGF-beta receptors: type I, type II, and type III.
Type I receptors, also known as ALK receptors, are serine/threonine kinases. They possess an intracytoplasmic kinase
Type II receptors are also serine/threonine kinases and are characterized by a longer extracellular domain and
Type III receptors, also known as betaglycan, are proteoglycans that act as co-receptors. They do not possess
The TGF-beta signaling pathway is involved in a wide range of cellular processes, including cell growth, differentiation,