Shigatoksiner
Shigatoksiner is a potent neurotoxin produced by the bacterium Shigella dysenteriae type 1, which is a leading cause of bacterial dysentery and bacillary dysentery. The toxin is responsible for the severe gastrointestinal symptoms associated with these infections, including abdominal pain, diarrhea, and sometimes bloody stools. Shigatoksiner acts by inhibiting the release of acetylcholine from motor neurons at the neuromuscular junction, leading to paralysis of the intestinal muscles and subsequent dysentery.
The toxin is composed of two subunits: A and B. The B subunit binds to gangliosides on
Shigatoksiner is highly specific for the bacterium Shigella dysenteriae type 1 and is not produced by other