ST6GalNAcFamilien
ST6GalNAcFamilien, also known as the sialyltransferase 6 family, is a group of enzymes that catalyze the transfer of sialic acid from a donor molecule to an acceptor molecule, specifically to the terminal N-acetylgalactosamine (GalNAc) residue of glycans. This family of enzymes plays a crucial role in the biosynthesis of complex glycans, which are involved in various biological processes such as cell-cell recognition, immune response, and signal transduction.
The ST6GalNAc family is characterized by their substrate specificity and the type of sialic acid they transfer.
Mutations in genes encoding ST6GalNAc enzymes have been associated with various diseases, including congenital disorders of
The ST6GalNAc family of enzymes is a vital component of the glycosylation machinery, and understanding their