SRCa2

SRCa2 is a gene that encodes a protein belonging to the SRC family of non-receptor tyrosine kinases. These kinases play crucial roles in regulating various cellular processes including cell growth, differentiation, survival, and migration. The SRC family of kinases is characterized by a conserved domain structure, typically including a unique N-terminal domain, an SH3 domain, an SH2 domain, and a catalytic kinase domain. SRC kinases are activated through autophosphorylation and are also regulated by inhibitory phosphorylation.

The SRCa2 protein is involved in signaling pathways that are important for maintaining normal cellular function. Aberrant SRCa2 activity has been implicated in the development and progression of various diseases, particularly cancer. In cancer cells, SRCa2 can be overexpressed or its activity can be dysregulated, contributing to uncontrolled proliferation, invasion, and metastasis. Consequently, SRCa2 has emerged as a potential therapeutic target for cancer treatment, with ongoing research focused on developing inhibitors that can selectively target its activity. Understanding the precise mechanisms by which SRCa2 exerts its effects and how its dysregulation contributes to disease is an active area of scientific investigation.