SMALPtechnológiával
SMALPtechnológia refers to Stable, Metal-Coated, Amphipathic, Lipid-Bags. This technology is a novel approach for encapsulating and delivering various molecules, particularly those that are difficult to work with in aqueous solutions. SMALPs are nanoscale vesicles formed from synthetic lipids and a small membrane protein, often a genetically engineered variant of a bacterial outer membrane protein. These components self-assemble in solution to create a stable, lipid-bilayer environment.
The key innovation of SMALP technology lies in the use of a metal-chelating tag, typically histidine residues,
The amphipathic nature of the lipids ensures the formation of a bilayer structure that mimics natural cell