SLC7A

SLC7A refers to a gene family that encodes solute carrier family 7 members. These are a group of transmembrane proteins that function as amino acid transporters. The SLC7A family plays a crucial role in the transport of various amino acids across cell membranes, including neutral, basic, and acidic amino acids. Different members of the SLC7A family exhibit distinct substrate specificities and cellular localizations, contributing to specialized physiological functions. For instance, some SLC7A transporters are involved in nutrient uptake in the intestine and kidneys, while others are critical for neurotransmitter transport in the brain. Mutations in SLC7A genes have been linked to a variety of human diseases, highlighting their importance in health. These diseases can manifest as aminoacidurias, neurological disorders, or other metabolic abnormalities depending on the specific transporter affected and its role in the body. Research into the SLC7A family continues to uncover their diverse functions and potential therapeutic targets.