ROBO2H

ROBO2H is a gene that encodes a protein involved in neural development. The protein, also known as roundabout homolog 2, is a member of the Robo family of transmembrane receptors. These receptors play a crucial role in guiding the growth and guidance of axons, which are the long projections of nerve cells. Specifically, ROBO2H is thought to be involved in the development of the central nervous system. It functions by interacting with secreted signaling molecules called Slits, which act as repulsive cues for growing axons. This interaction helps to ensure that axons navigate correctly to their target destinations. Mutations or alterations in the ROBO2H gene have been associated with various neurological conditions, although the exact mechanisms are still under investigation. Research into ROBO2H continues to shed light on the complex processes of neural circuit formation and the genetic underpinnings of neurological disorders. Its expression patterns and functional interactions are key areas of ongoing study in the field of neuroscience.