RANKLdependent
RANKLdependent is a term used in biology to describe cellular processes or biological phenomena that are reliant on the presence and activity of Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL). RANKL is a crucial protein that plays a significant role in the development and function of various cells, particularly osteoclasts, which are responsible for bone resorption.
When RANKL binds to its receptor, RANK, found on the surface of osteoclast precursors, it initiates a
Beyond bone metabolism, RANKL signaling is also implicated in the development and function of other cell types,