RAG5

RAG5, also known as Retinal Artery Occlusion Gene 5, is a gene located on human chromosome 1. While its precise function is still under investigation, preliminary research suggests it may play a role in vascular development and the regulation of blood flow. Mutations in the RAG5 gene have been associated with certain types of retinal artery occlusions, a condition where blood flow to the retina is blocked, potentially leading to vision loss.

Studies have identified several single nucleotide polymorphisms (SNPs) within the RAG5 gene that are being examined for their potential association with increased risk of cardiovascular diseases, including those affecting the eyes. The protein product of RAG5 is thought to be involved in cellular signaling pathways related to endothelial cell function, which are crucial for maintaining the health of blood vessels. Further research is ongoing to fully elucidate the molecular mechanisms by which RAG5 contributes to vascular health and disease. Understanding the role of RAG5 could potentially lead to new diagnostic tools or therapeutic strategies for conditions involving blood vessel abnormalities.