R15S

R15S, also known as R15S1, is a variant of the SARS-CoV-2 virus, which causes COVID-19. It was first identified in South Africa in April 2021 and has since been detected in several other countries. The variant is named for the mutations it contains, specifically a mutation in the spike protein (R) and a mutation in the N-terminal domain of the spike protein (15S). The 15S mutation is a deletion of 15 amino acids in the N-terminal domain of the spike protein, which is thought to increase the virus's ability to infect cells and evade immune responses.

R15S has been associated with an increased risk of severe disease and death, particularly in older adults and those with underlying health conditions. However, the overall impact of the variant on the global pandemic is still being studied. As of now, the World Health Organization has classified R15S as a variant of interest, meaning that it is being monitored for its potential impact on public health.

The variant has also been associated with a higher rate of transmission, which has led to concerns about its potential to drive new waves of infection. However, the extent of this increased transmissibility is still being studied. In response to the emergence of R15S, many countries have implemented public health measures, such as increased testing and contact tracing, to control the spread of the variant.

Overall, R15S is a variant of concern that has the potential to significantly impact the global pandemic. Continued monitoring and research are needed to better understand the variant's characteristics and to develop effective strategies for controlling its spread.