PKnew

PKnew is a software tool designed for analyzing and visualizing protein kinase interaction networks. It provides a platform for researchers to explore the complex relationships between different protein kinases and their substrates, as well as to identify potential drug targets. The software integrates data from various public databases, including UniProt, KinasePharma, and PDB, to create comprehensive network representations. Users can query the database to find specific kinases, substrates, or pathways of interest. PKnew offers several visualization options, allowing users to view networks in different layouts and to highlight specific features such as phosphorylation sites or disease associations. In addition to network visualization, the tool includes functionalities for data analysis, such as calculating network properties and identifying key regulatory nodes. The primary goal of PKnew is to facilitate a deeper understanding of kinase biology and to aid in the discovery of new therapeutic strategies for diseases involving kinase dysregulation. The development of PKnew aims to make complex kinase interaction data more accessible and interpretable for a wide range of users in the biological and biomedical research communities.