Mitosisadjacent

Mitosisadjacent is a neologism in cell biology used to refer to cellular processes that occur in close temporal or functional association with mitosis but are not strictly core mitotic events. The concept emphasizes the continuity between interphase and mitosis, and between mitosis and cytokinesis.

The term blends mitosis with adjacent, and it is not universally standardized; different authors may define its scope differently, sometimes including pre-mitotic preparations, spindle assembly checkpoint signaling, and post-mitotic resetting of cellular states.

Examples of mitosisadjacent processes include regulation of the G2/M transition, centrosome duplication and maturation, chromatin remodeling that prepares the genome for mitosis, transcriptional or epigenetic programs that interface with mitotic control, and signals coordinating cytokinesis with abscission.

Usage and interpretation: The lack of a standard definition means researchers apply the term variably; some use it to describe events tightly coupled to mitosis across species, others to emphasize regulatory links between mitotic and interphase states.

See also: cell cycle, mitosis, spindle assembly checkpoint, cytokinesis, abscission checkpoint.