Membranspeichern

Membranspeichern is a term used in cell biology to describe how membranes and membrane-bound organelles store and regulate substances. It covers the sequestration, retention and mobilization of ions, metabolites and signaling molecules within the endomembrane system and related structures.

Common storage sites include lysosomes, vacuoles, endosomes, secretory granules, and the endoplasmic/sarcoplasmic reticulum. Lipid droplets store neutral lipids and are enclosed by a phospholipid monolayer. The plasma membrane can also serve as a reversible reservoir for surface area and signaling lipids. Calcium ions are especially stored in the ER and sarcoplasmic reticulum.

Membranous storage supports ion homeostasis, metabolic regulation, vesicular trafficking and secretion. It is dynamically controlled by organelle biogenesis, vesicle fusion and membrane remodeling, responding to energy status and cellular signals. Storage processes interact with other aspects of cell physiology, such as synthesis, transport and degradation pathways.

Pathologies can arise from storage defects, including lysosomal storage disorders or disrupted calcium handling. In research, Membranspeichern informs studies of organelle dynamics, membrane trafficking and lipid metabolism, and it underpins biotechnological approaches to targeted delivery and controlled release.