Matriksiefektit
Matriksiefektit refers to phenomena observed in mass spectrometry where the ionization or detection of one analyte is influenced by the presence of other substances in the sample. This interference can lead to inaccurate quantitation or even the suppression or enhancement of the signal from the target analyte.
There are several types of matrix effects. Ion suppression occurs when the co-eluting matrix components reduce
The severity of matrix effects depends on various factors, including the ionization technique used, the specific
To mitigate matrix effects, several strategies can be employed. Thorough sample cleanup and purification, such as