MHCpohjaiset
MHCpohjaiset (Major Histocompatibility Complex class I molecules presenting peptides with C-terminal hydrophobic or cationic residues) are a class of subtypes of MHC class I molecules. These molecules play a crucial role in the immune system, specifically in the presentation of peptide antigens to T-cells.
Each MHC class I molecule consists of a heavy chain with three domains, alpha 1, alpha 2,
MHCpohjaiset bind peptides with hydrophobic or cationic residues at the C-terminus, and these residues are important
In contrast to MHC molecules that present peptides with hydrophilic or neutral residues at the C-terminus,
MHCpohjaiset have been implicated in various immune responses, and dysregulation of these molecules has been associated