METTL15

Mettl15 is a human gene that encodes a protein involved in the regulation of gene expression. The Mettl15 protein is a member of the methyltransferase family and has been implicated in the N6-methyladenosine (m6A) modification of RNA.

Research has shown that Mettl15 plays a crucial role in the development and function of cells, particularly in the nervous system. The m6A modification, which is mediated by the Mettl15 protein, has been shown to regulate various cellular processes, including mRNA stability, localization, and translation.

Studies have also implicated Mettl15 in the regulation of gene expression during development and disease. For example, alterations in Mettl15 expression have been linked to neurological disorders, such as schizophrenia and autism spectrum disorder.

In terms of molecular function, Mettl15 has been shown to interact with other proteins involved in the m6A modification complex. These interactions are thought to facilitate the recognition and modification of target RNAs, leading to changes in gene expression.

While the role of Mettl15 in human biology is still being studied, research has highlighted its importance as a regulatory element in the N6-methyladenosine pathway. Further investigation of Mettl15's function and regulation may provide insights into the underlying causes of diseases and lead to the development of novel therapeutic strategies. As research continues, a more comprehensive understanding of Mettl15's role in the regulation of gene expression will emerge.