MED12L

MED12L, also known as Mediator Complex Subunit 12 Like, is a gene that encodes a protein subunit of the Mediator complex. The Mediator complex is a large multi-protein assembly that plays a crucial role in regulating gene transcription. It acts as a bridge between transcription factors and the RNA polymerase II machinery, facilitating the initiation and elongation of gene expression.

The MED12L protein itself is thought to be involved in mediating interactions within the Mediator complex and with other regulatory proteins. While the precise functions of MED12L are still being investigated, studies suggest its involvement in various cellular processes, including development and differentiation. Aberrant expression or mutations in MED12L have been implicated in certain diseases, although this area requires further research. Genetic variations in MED12L have been associated with some congenital disorders, highlighting its importance in normal human development. Research into MED12L continues to uncover its complex roles in gene regulation and its potential involvement in human health and disease.