Ligandenträger

Ligandenträger is a German term that translates to "ligand carrier" or "ligand support" in English. It refers to a substance or molecule that holds or transports other molecules, specifically ligands, within a chemical system. This concept is particularly relevant in coordination chemistry and catalysis.

In coordination chemistry, a ligandenträger is often a larger molecular framework or a solid support to which ligands are attached. These immobilized ligands can then coordinate with metal ions, forming metal complexes. The purpose of using a ligandenträger can be to facilitate the separation of the catalyst from the reaction mixture, enabling easier recycling and reducing product contamination. This heterogeneous approach contrasts with homogeneous catalysis where the catalyst is dissolved in the same phase as the reactants.

Ligandenträger can also be employed in drug delivery systems. Here, the ligandenträger is a molecule designed to bind to specific biological targets, carrying attached drug molecules to the site of action. This targeted delivery aims to increase therapeutic efficacy while minimizing side effects by reducing the drug's exposure to healthy tissues. The nature of the ligandenträger can vary widely, from polymers and nanoparticles to biomolecules like antibodies. The specific design of a ligandenträger depends heavily on its intended application and the properties of the ligands it carries.