LeloirPathway
The Leloir pathway, also known as the pentose phosphate pathway, is a metabolic pathway that plays a crucial role in the production of NADPH, a coenzyme essential for various biosynthetic reactions, particularly in the synthesis of fatty acids and cholesterol. This pathway is particularly active in rapidly dividing cells, such as those found in the liver, and is also involved in the production of ribose-5-phosphate, a precursor for nucleotides.
The Leloir pathway begins with the oxidation of glucose-6-phosphate, which is catalyzed by glucose-6-phosphate dehydrogenase. This
One of the key features of the Leloir pathway is its ability to generate NADPH, which is
The Leloir pathway is regulated by several factors, including the availability of glucose and the cellular
The Leloir pathway is a fundamental metabolic pathway that plays a vital role in maintaining cellular redox