L7L12

L7L12 is a protein-coding gene located on the long arm of chromosome 12 at position 12q24.11. The gene is also known as Leucine-rich repeat-containing protein 71 or LRRC71. It is conserved in many species, including chimpanzees, dogs, cows, and rats, indicating its evolutionary importance.

The L7L12 gene encodes a protein that contains leucine-rich repeats, which are structural motifs involved in protein-protein interactions. The exact function of the L7L12 protein is not yet fully understood, but research suggests it may play a role in cellular processes such as signal transduction and cell adhesion. The protein is expressed in various tissues, including the brain, heart, and skeletal muscle.

Studies have linked L7L12 to certain diseases. For instance, variations in the L7L12 gene have been associated with an increased risk of developing type 2 diabetes mellitus. Additionally, altered expression of L7L12 has been observed in some cancer types, such as breast and lung cancer, although the precise role of the gene in these diseases remains to be elucidated.

Further research is needed to fully comprehend the biological functions of L7L12 and its potential implications in health and disease. Understanding the role of this gene could provide valuable insights into the molecular mechanisms underlying various physiological and pathological processes.