Kvinacrin

Kvinacrin, also known as mepacrine or quinacrine, is an antimalarial drug that has also been used for other conditions. It was first synthesized in 1928 and was widely used as an antimalarial during World War II. Kvinacrin belongs to the acridine class of compounds and works by interfering with the parasite's ability to digest hemoglobin.

In addition to its antimalarial properties, kvinacrin has been investigated and used for its anti-inflammatory and antiprotozoal effects. It has been employed in the treatment of giardiasis, a parasitic infection of the small intestine, and has also been explored for its potential in treating certain autoimmune diseases and as a topical agent for skin conditions.

The use of kvinacrin has declined significantly with the development of newer and more effective antimalarial drugs with fewer side effects. However, it remains a subject of research for its broader biological activities. Common side effects associated with kvinacrin include gastrointestinal disturbances, headache, and dizziness. In some cases, it can cause a yellow discoloration of the skin and urine. Its administration is typically oral.