KIF13As

KIF13A, also known as Kinesin Family Member 13A, is a protein that belongs to the kinesin superfamily of motor proteins. These proteins are crucial for intracellular transport, moving cargo along microtubule filaments within cells. KIF13A is characterized by its N-terminal motor domain, which binds to microtubules and hydrolyzes ATP to generate force, and a C-terminal domain that interacts with specific cargo.

Research indicates that KIF13A plays a significant role in various cellular processes, including organelle trafficking, cell division, and signal transduction. It has been implicated in the transport of vesicles containing specific receptors and signaling molecules. The precise cargo it transports and its specific functions are areas of ongoing investigation, but studies suggest its involvement in processes such as autophagy and the regulation of cell polarity.

Mutations or dysregulation of KIF13A have been associated with certain diseases, highlighting its importance in cellular homeostasis. Understanding the molecular mechanisms of KIF13A action and its interactions with other proteins is vital for elucidating its precise roles in health and disease. Continued research aims to further define its functional repertoire and explore its potential as a therapeutic target.