KCNS2

KCNS2, also known as KCN gene-related protein S2 or potassium voltage-gated channel subfamily S member 2, is a gene that encodes a protein involved in the regulation of potassium channels. These channels play a crucial role in the electrical excitability of cells, particularly in the nervous system and the heart. The protein produced by KCNS2 is a regulatory subunit, meaning it modifies the function of other, pore-forming potassium channel subunits.

Variations or mutations in the KCNS2 gene have been associated with certain neurological conditions. Research has explored its potential involvement in disorders such as epilepsy and other channelopathies, which are diseases caused by dysfunction of ion channels. The precise mechanisms by which KCNS2 influences neuronal activity and its contribution to disease pathogenesis are areas of ongoing scientific investigation. Understanding the role of KCNS2 is important for developing targeted therapies for these conditions.