Isocitric

Isocitric refers to a chemical compound that is a key intermediate in the citric acid cycle, also known as the Krebs cycle or TCA cycle. This cycle is a fundamental metabolic pathway found in the mitochondria of eukaryotic cells, where it plays a crucial role in energy production and the synthesis of certain biomolecules. The isocitric compound, specifically isocitrate, is formed from citrate through the action of the enzyme aconitase. Isocitrate is then converted into α-ketoglutarate by the enzyme isocitrate dehydrogenase, which is a critical step in the cycle as it generates NADH, a molecule essential for the production of ATP, the primary energy currency of the cell. The citric acid cycle is vital for the breakdown of carbohydrates, fats, and proteins, making it a cornerstone of cellular metabolism.