Immunphänotypische

Immunphänotypische refers to the characteristic set of antigens or surface molecules expressed by a cell. These antigens can be detected and analyzed using immunological techniques, most commonly flow cytometry or immunohistochemistry. By identifying and quantifying these markers, researchers and clinicians can determine the cell type, its developmental stage, and its functional state. This is particularly crucial in the field of hematology and oncology for classifying leukemia and lymphoma subtypes, monitoring treatment response, and identifying minimal residual disease. Beyond cancer diagnostics, immunophenotyping plays a role in transplant immunology to assess donor-recipient compatibility and in research to understand immune cell differentiation and function. The specific combination of antigens is unique to different cell populations, allowing for their precise identification and enumeration within a mixed sample.