IgDmediated
IgDmediated refers to biological processes or immune responses that are triggered or influenced by the antibody isotype immunoglobulin D (IgD). IgD is a type of antibody found on the surface of mature B lymphocytes, where it serves as a B cell receptor (BCR). While its exact functions are still being researched, IgD is believed to play a role in B cell activation, maturation, and tolerance.
Upon encountering an antigen, IgD on the surface of a B cell can bind to it. This
Furthermore, IgD is thought to be crucial in maintaining B cell homeostasis and preventing autoimmune reactions.