IL1F8

IL1F8, also known as IL36γ or IL1RAPL3, is a protein-coding gene that belongs to the Interleukin-1 (IL-1) family of cytokines. These cytokines are critical players in the immune system and inflammatory responses. The IL1F8 gene encodes a secreted protein that is believed to function as a signaling molecule, interacting with other members of the IL-1 family.

The exact biological functions of IL1F8 are still being actively researched. However, studies suggest it plays a role in modulating immune cell activity and contributing to inflammatory processes. Its expression has been detected in various tissues, including skin, lungs, and the central nervous system, indicating a potentially diverse range of physiological roles.

Dysregulation of IL1F8 has been implicated in certain diseases. For instance, alterations in its expression or function have been observed in inflammatory skin conditions, suggesting a link to the pathogenesis of these disorders. Further investigation is ongoing to fully elucidate the specific mechanisms by which IL1F8 influences health and disease, and to explore its potential as a therapeutic target.