IGHD
IGHD, also known as Immunoglobulin Heatdenaturation domain, is a specialized protein domain involved in the immune response. It is characterized by its role in the structural and functional aspects of immunoglobulins, commonly known as antibodies. The IGHD domain contributes to the stability and flexibility of antibody molecules, enabling them to recognize and bind to specific antigens effectively.
This domain is typically found within the variable regions of immunoglobulin heavy chains, where it participates
The IGHD domain is also significant in the processes of immunoglobulin gene rearrangement and somatic hypermutation,
Research into this domain continues to enhance understanding of antibody development, immune recognition, and potential therapeutic