HGNClisted

HGNClisted is a human gene nomenclature resource that provides a curated and approved list of human gene symbols and names. It is managed by the Human Genome Organisation (HUGO) Gene Nomenclature Committee (HGNC). The primary goal of HGNC is to assign a unique and meaningful symbol and name to every human gene. This standardization is crucial for clear communication in genetics and genomics research, facilitating database curation, literature indexing, and interdisciplinary collaboration.

The HGNC database is updated regularly to reflect new gene discoveries and revisions to existing gene nomenclature. Each gene entry includes the official HGNC symbol, the full gene name, alternative symbols or aliases, and links to relevant external databases such as Entrez Gene and Ensembl. The committee follows a set of guidelines for gene symbol assignment, aiming for symbols that are short, mnemonic, and avoid ambiguity. These guidelines have evolved over time to accommodate the increasing knowledge of the human genome. The HGNC also works to ensure that symbols are not easily confused with other gene symbols or common acronyms. Access to the HGNClisted database is typically available through the HGNC website, where researchers can search for specific genes or browse the entire approved nomenclature. This resource is fundamental for anyone working with human gene information, from basic researchers to clinical geneticists.