HEI10

HEI10 is a gene that encodes a protein involved in regulating cell division and chromosome segregation. This protein belongs to the IκB kinase family and plays a critical role in the DNA damage response pathway. When DNA is damaged, HEI10 is activated, which in turn initiates a cascade of events to repair the damage or trigger cell death if the damage is too severe.

The HEI10 protein is essential for maintaining genomic stability. Mutations or dysregulation of HEI10 have been linked to various human diseases, including certain types of cancer and developmental disorders. In cancer, HEI10's role in DNA repair can be exploited by tumors to survive and proliferate, making it a potential target for cancer therapies. Research into HEI10 continues to explore its precise mechanisms of action and its implications in various biological processes. Understanding HEI10's function is crucial for advancing our knowledge of cell cycle control, DNA repair, and disease pathogenesis.