Granulomatös

Granulomatös is a German medical term that describes a pathological condition characterized by the formation of granulomas. Granulomas are microscopic collections of immune cells, primarily macrophages, that group together in response to chronic inflammation or infection. These collections are typically surrounded by a layer of lymphocytes and other inflammatory cells. The purpose of granuloma formation is to wall off and contain persistent foreign substances or infectious agents that the body cannot readily eliminate.

The presence of granulomas, or a granulomatous process, can be indicative of a variety of underlying diseases. These can include infectious conditions such as tuberculosis, fungal infections, and leprosy, as well as non-infectious inflammatory conditions like sarcoidosis, Crohn's disease, and certain types of vasculitis. The specific characteristics of the granuloma, such as whether it is caseating (containing cheesy-like necrotic material) or non-caseating, can provide further clues to the underlying cause. Diagnosis often involves tissue biopsy and microscopic examination to identify and characterize the granulomas. Treatment strategies are dependent on the identified cause of the granulomatous inflammation.