Glukagonipitoisuus

Glukagonipitoisuus refers to the concentration of glucagon in the blood. Glucagon is a hormone produced by the alpha cells of the pancreas. Its primary role is to regulate blood glucose levels, acting in opposition to insulin. When blood glucose levels fall, such as between meals or during fasting, the pancreas releases glucagon. This hormone then signals the liver to break down stored glycogen into glucose, a process called glycogenolysis, and to synthesize new glucose from non-carbohydrate sources, a process called gluconeogenesis. The glucose is then released into the bloodstream, raising blood glucose levels back to a normal range.

Measuring glucagon levels can be important in diagnosing and managing certain medical conditions. For example, elevated glucagon levels can be seen in conditions like type 1 diabetes, particularly when blood glucose is low or when there is a lack of insulin. Conversely, in some cases of insulinoma, a tumor of the pancreatic beta cells that overproduces insulin, glucagon levels might be suppressed. Abnormal glucagon secretion can also contribute to hyperglycemia. The measurement is typically done through a blood test. Understanding glucagonipitoisuus is crucial for comprehending glucose homeostasis and the pathophysiology of metabolic disorders.