Glu102

Glu102 refers to Glutamate at position 102 within a protein sequence. Glutamate is one of the 20 standard amino acids, characterized by its acidic side chain containing a carboxyl group. The designation "Glu102" indicates that the amino acid at the 102nd position in the linear sequence of a specific protein is glutamate.

The specific properties and function of Glu102 are entirely dependent on the particular protein it resides in. Glutamate residues are often involved in a variety of roles within proteins. Due to their negative charge at physiological pH, they can participate in electrostatic interactions, binding to positively charged molecules or other protein residues. They can also act as catalytic residues in enzymes, facilitating chemical reactions through proton transfer or stabilization of transition states. Furthermore, glutamate can be involved in hydrogen bonding and can contribute to the overall three-dimensional structure and stability of the protein.

The importance of a specific Glu102 residue is often highlighted when it is part of a critical functional site, such as an active site in an enzyme or a binding site for a ligand. Mutations or modifications at this position can lead to altered protein function, potentially causing disease or affecting biological processes. Therefore, understanding the context of Glu102 within its protein is essential for comprehending its biological significance.