Geelimatriisi
Geelimatriisi refers to the substance that fills the space between cells in connective tissues. It is a complex mixture primarily composed of water, proteoglycans, and glycosaminoglycans (GAGs). These components are synthesized and secreted by resident cells within the connective tissue, such as fibroblasts. The geelimatriisi provides structural support to tissues, helps to resist compressive forces, and plays a crucial role in cell migration and signaling. Its composition can vary significantly depending on the specific type of connective tissue and its function. For instance, in cartilage, the geelimatriisi is rich in proteoglycans like aggrecan, which contributes to its high water content and shock-absorbing properties. In bone, the geelimatriisi is mineralized, providing rigidity. The fluid nature of the geelimatriisi allows for the diffusion of nutrients and waste products between blood vessels and cells. It also acts as a barrier to the passage of certain molecules, regulating the movement of substances within the tissue. Changes in the composition or organization of the geelimatriisi are associated with various pathological conditions, including inflammation and degenerative diseases. Understanding the structure and function of the geelimatriisi is essential for comprehending tissue homeostasis and disease processes.