GSK3A

GSK3A, also known as Glycogen Synthase Kinase 3 Alpha, is a gene that encodes a protein kinase. This enzyme belongs to the glycogen synthase kinase 3 (GSK3) family. GSK3A plays a role in a variety of cellular processes, including cell cycle regulation, apoptosis, and signal transduction. It is a serine/threonine kinase that phosphorylates numerous substrates, influencing their activity and function. The protein kinase activity of GSK3A is regulated by phosphorylation, and it is known to be involved in multiple signaling pathways, such as the Wnt signaling pathway and the PI3K/Akt pathway. Dysregulation of GSK3A has been implicated in various diseases, including neurodegenerative disorders like Alzheimer's disease and certain types of cancer. Research into GSK3A continues to explore its complex roles in normal physiology and disease pathogenesis, with a particular focus on its potential as a therapeutic target. The precise functions and interactions of GSK3A are still an active area of scientific investigation.