GRID2

GRID2 is a term that can refer to multiple, distinct topics in biology and entertainment. It is used to denote a human gene encoding a glutamate receptor subunit, and it is also the title of a racing video game released in 2013 by Codemasters. As a result, GRID2 does not have a single, unified article; context determines which topic is meant.

GRID2 stands for Glutamate Receptor, Ionotropic, Delta-2. The GRID2 gene encodes the delta-2 subunit of an ionotropic glutamate receptor, a member of the GluD family. The protein is predominantly expressed in the cerebellum, where it contributes to synapse formation, maturation, and maintenance, especially at parallel fiber–Purkinje cell synapses. Unlike classical glutamate receptors, GRID2 subunits are considered orphan receptors with nonconventional signaling; they participate in larger synaptic complexes in cooperation with other proteins, such as cerebellins and neurexins. Animal studies show that GRID2 function is important for normal motor coordination, while human disease associations are an area of ongoing research and are not yet fully resolved.

GRID 2 is a racing video game developed by Codemasters and released in 2013 as the sequel to GRID. It was published for multiple platforms, including PC, PlayStation 3, and Xbox 360. The game features a variety of licensed cars, diverse international locations, and multiple race modes, with an emphasis on accessible, arcade-like handling alongside realistic physics. GRID 2 supports online multiplayer and competitive play, and it was followed by subsequent titles in the GRID series.