GABATransporters
GABA transporters, also known as GATs, are a family of proteins responsible for the reuptake of gamma-aminobutyric acid (GABA) from the synaptic cleft into neurons and glial cells. GABA is the primary inhibitory neurotransmitter in the mammalian central nervous system, and its efficient removal from the synapse is crucial for regulating neuronal excitability and preventing excessive inhibition.
There are four known subtypes of GABA transporters: GAT1, GAT2, GAT3, and BGT1. Each subtype exhibits distinct
The function of GABA transporters is critical for maintaining the delicate balance of excitation and inhibition