Fibrinogeenistä

Fibrinogeenistä is a protein naturally found in the blood plasma of vertebrates. It plays a crucial role in the blood clotting process, also known as hemostasis. When a blood vessel is injured, fibrinogen undergoes a transformation to form fibrin, a fibrous protein. This fibrin forms a mesh-like network that traps blood cells and platelets, ultimately creating a stable blood clot. This clot seals the damaged vessel, preventing excessive blood loss. Fibrinogen is synthesized in the liver and its levels in the blood can be affected by various physiological conditions. For instance, inflammation and certain diseases can lead to an increase in fibrinogen levels, which is often considered a marker of inflammation or cardiovascular risk. Conversely, severe liver disease or malnutrition can result in decreased fibrinogen levels, impairing the blood's ability to clot. The conversion of fibrinogen to fibrin is catalyzed by the enzyme thrombin, which is also part of the clotting cascade. In summary, fibrinogen is an essential soluble protein in plasma that is converted into insoluble fibrin to form blood clots, a vital process for stopping bleeding.