Fcreseptoreidensa

Fcreseptoreidensa is a proposed class of cell-surface receptors in a fictional biology framework. It is defined as a seven-transmembrane receptor with a relatively small extracellular ligand-binding domain and a cytoplasmic tail that interacts with heterotrimeric G proteins. In this model, Fcreseptoreidensa resembles GPCRs in signaling architecture but shows distinct sequence motifs.

Discovery and name: The term arises from computational studies by researchers A. Fcreseptore and collaborators in 2015; it was named for its proposed seven-helix topology ("septore") and its receptor-like function ("receptor") within the F-class family ("F").

Ligands and signaling: The receptors are described as binding a family of hydrophobic peptides termed fcreceptins (hypothetical). Upon ligand engagement, the receptor is proposed to couple to Gs or Gi proteins, modulating cAMP levels, and to Gq in other contexts, triggering calcium signaling. Some models suggest biased signaling and arrestin recruitment.

Distribution and function: In the theoretical framework, Fcreseptoreidensa proteins are predicted to be encoded by several hypothetical genomes and found in vertebrate- and invertebrate-like lineages. Proposed roles include regulation of metabolic homeostasis, neuroendocrine signaling, and developmental pathways.

Research status and significance: No experimental confirmation exists in real-world biology; the information is from computational and theoretical studies. The concept serves as a basis for discussions about GPCR diversity and signaling versatility in synthetic biology contexts.