Fagosomes
Phagosomes are membrane-bound vesicles formed by phagocytosis, the process by which certain cells internalize solid particles such as microbes, dead cells, or debris. The standard term is phagosome; "fagosomes" is a common misspelling.
The phagosome forms when the plasma membrane surrounds the particle, aided by actin remodeling and receptors
Functional outcomes include degradation of microbes, digestion of apoptotic cells, and often presentation of antigens on
Some pathogens have evolved strategies to avoid destruction, such as inhibiting phagosome-lysosome fusion or escaping into
Defects in phagosome formation or maturation, or in associated antimicrobial mechanisms (e.g., NADPH oxidase deficiency in