Enzalutamid

Enzalutamid is an orally administered medication used to treat prostate cancer. It belongs to a class of drugs known as androgen receptor inhibitors. Enzalutamid works by blocking the action of androgens, such as testosterone, which are hormones that can fuel the growth of prostate cancer cells. It prevents androgens from binding to the androgen receptor, thereby inhibiting the signaling pathways that promote cancer cell proliferation and survival.

The drug is indicated for men with castration-resistant prostate cancer, a form of the disease that continues to grow despite treatment with hormone therapy that lowers testosterone levels. It is also used in some cases of metastatic hormone-sensitive prostate cancer. Enzalutamid is taken as a capsule. Common side effects may include fatigue, hot flashes, diarrhea, headache, and high blood pressure. More serious side effects can occur, and patients should discuss potential risks and benefits with their healthcare provider. The effectiveness and safety of enzalutamid have been established through clinical trials. It is typically prescribed by oncologists and urologists.