ELP4

Elp4 is a gene that encodes a protein involved in embryonic development. The protein, also known as ELP4, is a component of the elongator complex, a highly conserved multi-subunit protein complex found in eukaryotes. The elongator complex plays a crucial role in transcription elongation and DNA repair. Specifically, Elp4 is a subunit that interacts with other elongator proteins, contributing to the complex's overall stability and function.

Mutations or disruptions in the ELP4 gene have been associated with developmental abnormalities. In humans, mutations in genes related to the elongator complex have been linked to certain congenital disorders. Research in model organisms has further elucidated the importance of Elp4 in various developmental processes, including neural development and organogenesis. The precise mechanisms by which Elp4 and the elongator complex exert their influence are still areas of active investigation. Understanding the function of Elp4 is important for comprehending fundamental cellular processes and for potentially identifying targets for therapeutic interventions in developmental disorders.