EEA1C

EEA1C is a gene that encodes a protein involved in early endosome trafficking. The protein, also known as EEA1, is a crucial component of the endocytic pathway, which cells use to internalize molecules from their external environment. EEA1C is known to bind to phosphatidylinositol 3-phosphate (PI3P), a lipid that is enriched in early endosomes and plays a key role in vesicle fusion and protein sorting. This interaction helps to recruit other proteins to the early endosome membrane, facilitating the maturation of endosomes and their subsequent fusion with other cellular compartments.

Mutations or dysregulation of EEA1C have been associated with various cellular processes, including nutrient uptake, receptor recycling, and the regulation of signaling pathways. Its role in endosome trafficking makes it a potential target for understanding and treating diseases where these processes are compromised. Research into EEA1C continues to shed light on the intricate mechanisms of intracellular transport and its impact on cellular health and disease.