Dopaminisk

Dopaminisk is an adjective used in some languages to denote relations to dopamine, the brain neurotransmitter, or to the dopaminergic system. In English, the equivalent term is dopaminergic. The word may appear in neuroscience, pharmacology, and medical texts to describe neurons, receptors, or pharmacological actions that involve dopamine.

Dopamine is a monoamine neurotransmitter synthesized from the amino acid tyrosine. It is produced by dopaminergic neurons and released into synapses where it binds to dopamine receptors. Receptors are grouped into D1-like (D1, D5) and D2-like (D2, D3, D4) families, mediating excitatory or inhibitory signals. Dopamine action is terminated primarily by reuptake via the dopamine transporter and metabolism by monoamine oxidase and catechol-O-methyltransferase.

Dopaminergic signaling modulates movement, reward, motivation, mood, and endocrine control. Disturbances are linked to several disorders: degeneration of nigrostriatal neurons causes Parkinson’s disease; dysregulation in mesolimbic and mesocortical circuits is implicated in schizophrenia and substance use disorders. Pharmacological agents acting on the dopaminergic system include L-DOPA and dopamine agonists for deficit states, and antagonists for psychosis. Dopamine receptors and transporters are common targets for imaging and research.

Usage note: while "dopaminisk" may appear in some contexts, most English-language literature uses "dopaminergic" or "dopamine-related" to describe chemical, cellular, and clinical aspects.