Dmannose8phosphate

D-mannose-8-phosphate is a phosphorylated form of the sugar D-mannose. It is an intermediate in the metabolic pathway of D-mannose, specifically in the conversion of D-mannose to D-fructose-6-phosphate. This pathway is known as the D-mannose metabolic pathway. In biological systems, D-mannose-8-phosphate plays a role in carbohydrate metabolism. It is synthesized from D-mannose through the action of an enzyme, typically a mannose kinase, which adds a phosphate group to the molecule. Subsequently, D-mannose-8-phosphate is isomerized to D-fructose-6-phosphate by an enzyme called phosphomannose isomerase. D-fructose-6-phosphate is a key intermediate in glycolysis, the breakdown of glucose for energy. Therefore, the D-mannose metabolic pathway, including the formation and further processing of D-mannose-8-phosphate, provides a route for the body to utilize D-mannose as an energy source. The presence and levels of D-mannose-8-phosphate can be indicative of metabolic activity related to D-mannose processing.