DisseminierteIntravaskuläre

Disseminierte intravaskuläre koagulation, commonly known as DIC, is a severe medical condition characterized by the formation of blood clots throughout the body's blood vessels. This condition is often triggered by severe trauma, surgery, or certain medical conditions such as sepsis, cancer, or pregnancy complications. DIC can lead to widespread bleeding, organ failure, and even death if not promptly treated.

The primary mechanism of DIC involves the activation of the coagulation cascade, leading to the consumption of clotting factors and platelets. This results in a hypercoagulable state, where blood clots form in small blood vessels, blocking blood flow to vital organs. Additionally, DIC can cause microvascular thrombosis, leading to widespread bleeding and tissue damage.

Diagnosis of DIC typically involves laboratory tests that measure clotting factors, fibrinogen levels, and platelet counts. Imaging studies such as CT scans or MRIs may also be used to assess organ involvement. Treatment of DIC focuses on addressing the underlying cause, managing bleeding, and supporting organ function. This may include blood transfusions, medications to control clotting, and supportive care to prevent organ failure.

DIC is a medical emergency that requires immediate attention. Early recognition and prompt treatment are crucial for improving outcomes. Despite advances in medical care, DIC remains a significant cause of morbidity and mortality, highlighting the need for continued research into its prevention and treatment.