Dekarboxüleerimisreaktsioonid
Dekarboxylation is a chemical reaction that removes a carboxyl group (−COOH) from a molecule, releasing it as carbon dioxide (CO2). This process is a type of elimination reaction. Dekarboxylation can occur through various mechanisms, often requiring specific conditions like heat or the presence of catalysts. For example, heating carboxylic acids can lead to their decarboxylation. Certain types of compounds are particularly prone to decarboxylation. Beta-keto acids, for instance, readily decarboxylate upon gentle heating, often without the need for additional catalysts, due to the proximity of the carbonyl group to the carboxyl group, which stabilizes the transition state.
This reaction is significant in organic chemistry and biochemistry. In biological systems, decarboxylation is a crucial