DCTN5

DCTN5, also known as dynactin subunit 5, is a protein-coding gene. It is part of the dynactin complex, a multiprotein complex that is essential for the function of cytoplasmic dynein. Cytoplasmic dynein is a motor protein that plays a critical role in intracellular transport, including the movement of organelles, vesicles, and chromosomes. The dynactin complex is thought to link dynein to its cargo and to the microtubules along which it moves.

The DCTN5 gene is located on chromosome 17 and encodes a protein of approximately 49 kilodaltons. This protein is expressed in a wide variety of tissues and cell types. While the precise role of DCTN5 within the dynactin complex is still being investigated, it is believed to contribute to the structural integrity and overall function of the complex. Mutations in DCTN5 have been associated with certain neurological disorders, although further research is needed to fully understand these links. Studying DCTN5 and its role in the dynactin complex is important for understanding fundamental cellular processes and for potentially developing therapeutic strategies for diseases involving disrupted intracellular transport.