DBCOlactones
DBCOlactones are a class of organic compounds that combine the chemical functionalities of dibenzocyclooctynes (DBCOs) and lactones. Dibenzocyclooctynes are strained alkyne-containing macrocycles known for their high reactivity in copper-free click chemistry, particularly with azides. Lactones are cyclic esters. The presence of both these features within a single molecule makes DBCOlactones valuable reagents in chemical synthesis and bioconjugation.
The core structure of a DBCOlactone involves a dibenzocyclooctyne ring system that also incorporates an ester
DBCOlactones have found utility in areas such as drug delivery and the synthesis of complex molecules. For