Csl4

Csl4 is a gene that encodes a protein involved in cell division. The protein produced by the Csl4 gene is known as centrosome-linked protein, and it plays a crucial role in the formation and function of centrosomes. Centrosomes are essential organelles in eukaryotic cells that act as the main microtubule organizing centers. They are involved in the assembly of the spindle apparatus during mitosis and meiosis, which is critical for the accurate segregation of chromosomes into daughter cells.

The Csl4 protein is primarily found in the cytoplasm and is known to interact with other proteins that are also involved in cell cycle regulation and chromosome segregation. Its precise molecular function is still under investigation, but research suggests it may be involved in organizing microtubules or in the recruitment of other proteins to the centrosome. Defects or mutations in the Csl4 gene have been associated with various cellular abnormalities, including aneuploidy (an abnormal number of chromosomes) and potential links to developmental disorders and cancer in some model organisms. Further research is ongoing to fully elucidate the role of Csl4 in normal cell division and its implications in disease.